Independent · Printed Daily · Est. 2026

The Daily Dispatch

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FDA approves first daily pill to cut cholesterol the way injectable PCSK9 drugs do

The FDA approved Lipfendra (enlicitide) on July 16, the first oral PCSK9 inhibitor for adults with high LDL cholesterol. PCSK9 inhibitors work by helping the liver clear "bad" cholesterol from the blood, but until now the drug class was only available as an injection, which put many patients off. Two large trials found Lipfendra could cut LDL levels by more than half with a strong safety profile. Merck says doctors should be able to start prescribing the pill within weeks, at a list price of $315 for a 30-day supply, with lower costs for insured patients and support planned for the uninsured. Researchers are already testing a one-time gene-editing therapy aimed at lowering bad cholesterol for life using the same PCSK9 target.

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UN forum: over half the world's population now has some form of social protection, a first

The UN's High-Level Political Forum on Sustainable Development, meeting in New York through July 15, highlighted a milestone in the ILO's World Social Protection Report: 52.4% of people worldwide were covered by at least one cash social protection benefit, such as a pension, child benefit or unemployment support, as of 2023 — up from 42.8% in 2015 and the first time coverage has passed the halfway mark. The forum closed with a ministerial declaration renewing member states' commitment to accelerate progress on the Sustainable Development Goals. Officials cautioned that 3.8 billion people remain entirely unprotected, but the reversal of decades of stagnant coverage was cited as evidence that expanding social protection systems, especially in lower-income countries, is achievable within a generation.

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California's grid shatters back-to-back solar and battery records as clean energy surges

California's power grid operator CAISO logged two records within 24 hours in early July: on July 9 the state's battery fleet discharged a record 12.99 gigawatts in the evening, more electricity than New York City draws on a hot summer day, and on July 10 solar generation hit a record 23 gigawatts, supplying 72% of regional demand at its peak — the third time California broke its own solar record since June 1. The milestones cap a record-setting first half of 2026 for US clean energy, in which solar and storage supplied 91% of all new grid capacity added in the first quarter and solar generated more electricity than coal nationwide for the first time in US history in May.

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